(2S,3S)-1-tert-Butoxycarbonyl-3-(5-(1-cyano-2,2,2-trifluoro-1-methylethyl)-2-methoxybenzyl)amino-2-phenylpiperidine → (2S,3S)-3-(5-(1-Cyano-2,2,2-trifluoro-1-methylethyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride
Reaktionsgleichung
C(OC([N:8]1[CH2:13][CH2:12][CH2:11][C@H:10]([NH:14][CH2:15][C:16]2[CH:21]=[C:20]([C:22]([C:28]#[N:29])([CH3:27])[C:23]([F:26])([F:25])[F:24])[CH:19]=[CH:18][C:17]=2[O:30][CH3:31])[C@@H:9]1[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1)=O)(C)(C)C.[ClH:38].Cl.COC1C=CC(C(C2SCCS2)(C)C)=CC=1CN[C@H]1CCCN[C@H]1C1C=CC=CC=1>>[ClH:38].[ClH:38].[C:28]([C:22]([C:20]1[CH:19]=[CH:18][C:17]([O:30][CH3:31])=[C:16]([CH:21]=1)[CH2:15][NH:14][C@H:10]1[CH2:11][CH2:12][CH2:13][NH:8][C@H:9]1[C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1)([CH3:27])[C:23]([F:24])([F:25])[F:26])#[N:29]Komponenten
3
Edukt 2
Produkt 1
Versuchsvorschrift
This compound was prepared from Compound 94 in the same manner of Compound 83.