Thionyl Chloride → 2-(7-Methoxynaphthalen-1-yl)acetyl chloride
Reaktionsgleichung
[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([OH:16])=O)=[CH:5][CH:4]=1.S(Cl)([Cl:19])=O>C(Cl)(Cl)Cl>[CH3:1][O:2][C:3]1[CH:12]=[C:11]2[C:6]([CH:7]=[CH:8][CH:9]=[C:10]2[CH2:13][C:14]([Cl:19])=[O:16])=[CH:5][CH:4]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The (7-methoxynaphth-1-yl)acetic acid obtained above is dissolved by heating in 300 ml of chloroform. The mixture is heated under reflux, and then thionyl chloride is added dropwise. The mixture is refluxed for two hours and evaporated to dryness. An oil is obtained which crystallizes on cooling. The residue obtained is used as such in the following stage.
Aufarbeitung
- dissolutionabove is dissolved
- temperatureThe mixture is heated
- temperatureunder reflux
- temperatureThe mixture is refluxed for two hours
- customevaporated to dryness
- customAn oil is obtained which
- customcrystallizes
- temperatureon cooling
- customThe residue obtained
Quellen und Nachweise
- ORD-Eintrag
- ord-a5644afb33d14df0ac29383062107646
- Quelldatensatz
- uspto-grants-1993_07
- Patentnummer
- US05225442
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