Methanol, 1-methoxy-, 1-acetate → 1,3-Dipivaloyl-2-methoxymethyl glycerol

HRID 483674Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 483674
[C:1]([O:7][CH2:8][CH:9]([CH2:11][O:12][C:13](=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15])[OH:10])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3].O.C1(C)C=CC(S(O)(=O)=O)=CC=1.[C:31]([O:34][CH2:35]OC)(=O)C>CCCCCC>[C:1]([O:7][CH2:8][CH:9]([CH2:11][O:12][C:13](=[O:18])[C:14]([CH3:17])([CH3:16])[CH3:15])[O:10][CH2:31][O:34][CH3:35])(=[O:6])[C:2]([CH3:5])([CH3:4])[CH3:3]

Komponenten

5

Edukt 3

HCID 78087Methanol, 1-methoxy-, 1-acetateHCID 521998p-Toluenesulfonic acid monohydrateHCID 136911551,3-Dipivaloyl glycerol

Produkt 1

HCID 109796251,3-Dipivaloyl-2-methoxymethyl glycerol

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8058HexaneLösungsmittel

Versuchsvorschrift

50.45 g of 1,3-dipivaloyl glycerol was dissolved in 200 ml of methoxymethyl acetate. After the addition of 2.5 g of p-toluenesulfonic acid monohydrate, the mixture was stirred for 1 hr then diluted with 200 ml of hexane and washed twice with 200 ml saturated aqueous sodium carbonate, once with aqueous NaCl solutions, dried over anhydrous magnesium sulfate and concentrated in vacuo to afford 1,3-dipivaloyl-2-methoxymethyl glycerol as a colorless oil.

Aufarbeitung

  1. washwashed twice with 200 ml saturated aqueous sodium carbonate, once with aqueous NaCl solutions
  2. dry with materialdried over anhydrous magnesium sulfate
  3. concentrationconcentrated in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-ce832fdd316046a394efeca9e7a52d66
Quelldatensatz
uspto-grants-1993_07
Patentnummer
US05225590

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