Dimethylamine → 4-Cyclohexyl-2-[(dimethylamino)methyl]-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one oxalate

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	Dimethylamine	HCID 674	—
Edukt	Oxalic Acid	HCID 971	—
Edukt	chloromethyl-4-cyclohexyl-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one	HCID 13729322	—
Lösungsmittel	Isopropanol	HCID 3776	—
Produkt	4-Cyclohexyl-2-[(dimethylamino)methyl]-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one oxalate	HCID 21271464	—

Reaktionsschritte

Utilizing the procedure of Example 10, 2-(chloromethyl-4-cyclohexyl-2,3-dihydropyrido[3,2-f][1,4]oxazepin-5(4H)-one (Intermediate 35) is reacted with 40% aqueous dimethylamine and reacted with oxalic acid in isopropyl alcohol.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US04727152
Quelldatensatz	uspto-grants-1988_02
ORD ID	ord-9d782d8069744710b9a22aaa91c12169
Quellennotiz	uspto-grants-1988_02