4-(4-Fluorophenyl)-1,2,3,6-tetrahydropyridine → 4-(4-Fluorophenyl)-1-[1-(4-nitrophenyl)-4-piperidinyl]-1,2,5,6-tetrahydropyridine
Reaktionsgleichung
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][C:13](=O)[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH2:29][CH2:28][NH:27][CH2:26][CH:25]=2)=[CH:20][CH:19]=1>>[F:17][C:18]1[CH:23]=[CH:22][C:21]([C:24]2[CH2:29][CH2:28][N:27]([CH:13]3[CH2:14][CH2:15][N:10]([C:7]4[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=4)[CH2:11][CH2:12]3)[CH2:26][CH:25]=2)=[CH:20][CH:19]=1Komponenten
3
Versuchsvorschrift
5.5 g of 1-(4-nitrophenyl)-4-piperidone and 4.4 g of 4-(4-fluorophenyl)-1,2,5,6-tetrahydropyridine were reacted as in Example 1. The product crystallized as fumarate.
Aufarbeitung
- customThe product crystallized as fumarate
Quellen und Nachweise
- ORD-Eintrag