HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,2,4-Trifluoro-5-nitrobenzene → 8,9-Difluoro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,2,4-Trifluoro-5-nitrobenzene | HCID 75012 | — |
| Edukt | 4-((Benzyloxy)carbonyl)piperazine-2-carboxylic acid | HCID 5058362 | — |
| Produkt | 8,9-Difluoro-2,3,4,4a-tetrahydro-1H,6H-pyrazino[1,2-a]quinoxalin-5-one | HCID 9882045 | 16,7% |
Reaktionsschritte
By the same procedure described for example 2 method 2B, from 1.5 g of racemic 4-carbobenzyloxypiperazine-2-carboxylic acid and 1,2,4-trifluoro-5-nitrobenzene, there was obtained 0.4 g (16.7%) of title compound as an orange-red residue.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06706714B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-15095fe4100943f68d9749222a8606f2 |
| Quellennotiz | uspto-grants-2004_03 |