Ethyl α-(acetylamino)-6-quinolinepropanoate → HCID 21925070, Verbindung

HRID 491284Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 491284
C([O:3][C:4](=[O:21])[CH:5]([CH2:10][C:11]1[CH:12]=[C:13]2[C:18](=[CH:19][CH:20]=1)[N:17]=[CH:16][CH:15]=[CH:14]2)[NH:6]C(=O)C)C>Cl>[N:17]1[C:18]2[C:13](=[CH:12][C:11]([CH2:10][CH:5]([C:4]([OH:21])=[O:3])[NH2:6])=[CH:20][CH:19]=2)[CH:14]=[CH:15][CH:16]=1

Komponenten

3

Edukt 1

HCID 21925091Ethyl α-(acetylamino)-6-quinolinepropanoate

Produkt 1

HCID 21925070HCID 21925070, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

N-Acetyl β-(6-quinolinyl)-D,L-alanine ethyl ester (728 mg, 2.55 mmol) was heated at reflux in 6N HCl (20 mL). After 20 h, the reaction mixture vas concentrated to dryness and the residue was dried in vacuo to provide the title compound, which was used directly in the next reaction.

Aufarbeitung

  1. concentrationthe reaction mixture vas concentrated to dryness
  2. customthe residue was dried in vacuo

Quellen und Nachweise

ORD-Eintrag
ord-87a38af366f242c18772660cac523008
Quelldatensatz
uspto-grants-2009_05
Patentnummer
US07531526B2

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