4-(2-Bromoethyl)benzoic acid → (3-Bromomethyl-phenyl)-acetic acid methyl ester
Reaktionsgleichung
[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([OH:12])=[O:11])[CH:6]=[CH:7][CH:8]=1.Br[CH2:14]CC1C=CC(C(O)=O)=CC=1>>[Br:1][CH2:2][C:3]1[CH:4]=[C:5]([CH2:9][C:10]([O:12][CH3:14])=[O:11])[CH:6]=[CH:7][CH:8]=1Komponenten
3
Versuchsvorschrift
According to the procedures described in the synthesis method of Intermediate ia-01, 2-[3-(bromomethyl)phenyl]acetic acid (500 mg) synthesized according to the procedures described in International Patent Publication WO00/03980 was used instead of 4-(2-bromoethyl)benzoic acid, and the material was reacted and treated to obtain the title compound (Intermediate il-01, 471 mg).
Aufarbeitung
- customdescribed in the synthesis method of Intermediate ia-01
- customthe material was reacted
- additiontreated
Quellen und Nachweise
- ORD-Eintrag
- ord-e81e3e2667644b58b5b66d36e6efaf1e
- Quelldatensatz
- uspto-grants-2009_05
- Patentnummer
- US07531533B2
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