Ammonium Acetate → 1-Amino-5-(2,5-difluorophenyl)cyclohexan-3-one

Beteiligte Stoffe

Reaktionsschritte

A solution of 5-(2,5-difluorophenyl)cyclohexane-1,3-dione (4.0 g) and ammonium acetate (4.1 g) in ethanol (60 ml) was heated under reflux for 12 hours. The reaction mixture was concentrated under reduced pressure, and the residue was washed with water and dried to obtain 1-amino-5-(2,5-difluorophenyl)cyclohexan-3-one (3.7 g).

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