HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Sodium hydride → 2-{[2-(Allyloxy)-4-(benzyloxy)phenoxy]methyl}oxirane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | Glycidyl tosylate, (R)- | HCID 154187 | — |
| Edukt | 2-Allyloxy-4-(benzyloxy)phenol | HCID 18546012 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Lösungsmittel | Hexane | HCID 8058 | — |
| Produkt | 2-{[2-(Allyloxy)-4-(benzyloxy)phenoxy]methyl}oxirane | HCID 18546022 | — |
Reaktionsschritte
Sodium hydride (4.3 g, 0.11 mole of 60% mineral oil dispersion) was washed with hexane and suspended in 100 mL of N,N-dimethylformamide. To this suspension was added a solution of 25.4 g (0.10 mole) of 2-allyloxy-4-(benzyloxy)phenol in 100 mL of DMF. The mixture was stirred at room temperature for 30 minutes and then 22.8 g (0.10 mole) of (2R)-(−)-glycidyl tosylate was added.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06706736B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-6233de2de6f143688edd4dcfaa46e9b9 |
| Quellennotiz | uspto-grants-2004_03 |