Ethanol → 2(1H)-Quinoxalinone
Reaktionsgleichung
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].[CH3:9][CH2:10][OH:11]>>[NH:7]1[C:2]2[C:1](=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:8]=[CH:9][C:10]1=[O:11]Komponenten
3
Versuchsvorschrift
A mixture of the 1,2-phenylene-diamine derivative (1 g) and the 2-oxo-carboxylic acid derivative (1 eq) in dry EtOH (35 mL) was stirred at reflux for 2 h under nitrogen. After cooling, the EtOH was evaporated to give a crude brown solid. Recrystallisation from EtOH gave the desired quinoxalin-2-one derivative.
Aufarbeitung
- temperatureat reflux for 2 h under nitrogen
- temperatureAfter cooling
- customthe EtOH was evaporated
- customto give a crude brown solid
- customRecrystallisation from EtOH
Quellen und Nachweise
- ORD-Eintrag
- ord-e11bf6e15ac14fa9a03e91a18f60a7dd
- Quelldatensatz
- uspto-grants-2009_05
- Patentnummer
- US07538109B2
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