7-Aminoquinoline → 6-Chloro-N-quinolin-7-yl-nicotinamide

Beteiligte Stoffe

Reaktionsschritte

Using the procedure outlined in Example 45, the title compound was prepared from 7-aminoquinoline (D55) (213 mg, 1.48 mmol) and 6-chloronicotinic acid (279 mg, 1.77 mmol) as a cream solid (405 mg). 1H NMR (250 MHz, CDCl3) δ (ppm): 8.94 (m, 2H), 8.24 (m, 2H), 8.16 (d, 1H), 8.14 (br.s, 1H), 8.01 (dd, 1H), 7.87 (d, 1H), 7.51 (d, 1H), 7.39 (dd, 1H).

Herkunft & Nachweise