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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 494238Erstellt: 24. Oktober 2026

2,6-Dimethylphenylboronic acid → 2',6'-Dimethyl-N-quinolin-7-yl-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/de/reaction/494238

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2,6-Dimethylphenylboronic acidHCID 583322—
Edukt4-bromo-N-quinolin-7-ylbenzamideHCID 831408—
Produkt2',6'-Dimethyl-N-quinolin-7-yl-1,1'-biphenyl-4-carboxamideHCID 57682675—

Reaktionsschritte

Using the procedure outlined in Example 58, the title compound was prepared from 4-bromo-N-quinolin-7-ylbenzamide (Example 82) (50 mg, 0.153 mmol) and 2,6-dimethyl-phenylboronic acid (25 mg, 0.17 mmol) as a white solid. 1H NMR (400 MHz, CDCl3) δ (ppm): 8.92 (dd, 1H), 8.20 (d, 1H), 8.14 (m, 3H), 8.02, (d, 2H), 7.87 (d, 1H), 7.37 (dd, 1H), 7.34 (d, 2H), 7.21 (t, 1H), 7.14 (d, 2H), 2.05 (s, 6H).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07538121B2
Quelldatensatzuspto-grants-2009_05
ORD IDord-bf000f578d3d41449fd2250791ab27eb
Quellennotizuspto-grants-2009_05