7-Aminoquinoline → HCID 57682719, Verbindung

Beteiligte Stoffe

Reaktionsschritte

Using the procedure outlined in Example 56, the title compound was prepared from 7-aminoquinoline (D55) (11 mg, 0.076 mmol) and 6-(4-fluorophenyl)-2-(methoxymethyl)-nicotinic acid (D86) (19 mg, 0.073 mmol) as an orange solid. 1H NMR (250 MHz, CDCl3) δ (ppm): 10.40 (br.s, 1H), 8.92 (dd, 1H), 8.41 (d, 1H), 8.29 (d, 1H), 8.05-8.20 (m, 4H), 7.85 (m, 2H), 7.36 (dd, 1H), 7.20 (t, 2H), 4.91 (s, 2H), 3.68 (s, 3H).

Herkunft & Nachweise