Diethyl 2-(2-phenyl-2-propylpentanoyl)malonate → Ethyl 1-hydroxy-4,4-dimethyl-3-oxo-3,4-dihydro-2-naphthalenecarboxylate
Reaktionsgleichung
[CH3:1][C:2]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)([CH3:16])[C:3]([CH:5]([C:11]([O:13]CC)=O)[C:6]([O:8][CH2:9][CH3:10])=[O:7])=[O:4].C1(C(CCC)(CCC)C(C(C(OCC)=O)C(OCC)=O)=O)C=CC=CC=1>>[OH:13][C:11]1[C:18]2[C:17](=[CH:22][CH:21]=[CH:20][CH:19]=2)[C:2]([CH3:16])([CH3:1])[C:3](=[O:4])[C:5]=1[C:6]([O:8][CH2:9][CH3:10])=[O:7]Komponenten
3
Versuchsvorschrift
The title compound was prepared according to the procedure of Example 1F, substituting the product of Example 9D for the product of Example 1E. 1H NMR (300 MHz, CDCl3): δ 15.16, 15.03 (two s, 1 H), 8.18 (m, 1 H), 7.52 (m, 3 H), 4.47 (m, 2 H), 1.66 (s, 3H), 1.51 (s, 3 H), 1.45 (t, J=6.62 Hz, 3 H).
Quellen und Nachweise
- ORD-Eintrag
- ord-55c7265aa36c429882581bdc053a8b7d
- Quelldatensatz
- uspto-grants-2009_05