Ethyl 1-hydroxy-3-oxo-4,4-dipropyl-3,4-dihydro-2-naphthalenecarboxylate → 1,1-dipropyl-4-hydroxy-2(1H)-naphthalenone
Reaktionsgleichung
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:15][CH2:16][CH3:17])([CH2:12][CH2:13][CH3:14])[C:4](=[O:18])[C:3]=1C(OCC)=O.C(C1(CCCC)C2C(=CC=CC=2)C(O)=C(C(OCC)=O)C1=O)CCC>>[CH2:15]([C:5]1([CH2:12][CH2:13][CH3:14])[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[C:2]([OH:1])=[CH:3][C:4]1=[O:18])[CH2:16][CH3:17]Komponenten
3
Versuchsvorschrift
The title compound was prepared according the procedure of Example 5B, substituting the product of Example 1F for the product of Example 4F. 1H NMR (300 MHz, CDCl3) δ ppm 0.55 (m, 2H) 0.67 (m, 4.8H) 0.79 (m, 1.2H) 0.98 (m, 2H) 1.78 (m, 2H) 2.19 (m, 2H) 3.69 (s, 0.4H) 6.13 (s, 0.8H) 7.41 (m, 2H) 7.56 (m, 0.8H) 7.67 (m, 0.2H) 8.07 (m, 0.2H) 8.13 (m, 0.8H).
Quellen und Nachweise
- ORD-Eintrag
- ord-69460d1c5c9648fda6fff1fdc8502782
- Quelldatensatz
- uspto-grants-2009_05
- Patentnummer
- US07538105B2
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