Hexyl chloroformate → 6-(4-Diethylamino-butoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid hexyl ester

HRID 49486Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 49486
[CH2:1]([N:3]([CH2:19][CH3:20])[CH2:4][CH2:5][CH2:6][CH2:7][O:8][C:9]1[CH:10]=[C:11]2[C:16](=[CH:17][CH:18]=1)[NH:15][CH2:14][CH2:13][CH2:12]2)[CH3:2].[CH2:21]([O:27][C:28](Cl)=[O:29])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[CH2:21]([O:27][C:28]([N:15]1[C:16]2[C:11](=[CH:10][C:9]([O:8][CH2:7][CH2:6][CH2:5][CH2:4][N:3]([CH2:1][CH3:2])[CH2:19][CH3:20])=[CH:18][CH:17]=2)[CH2:12][CH2:13][CH2:14]1)=[O:29])[CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]

Komponenten

3

Edukt 2

HCID 22466Hexyl chloroformateHCID 21966664Diethyl-[4-(1,2,3,4-tetrahydro-quinolin-6-yloxy)-butyl]-amine

Produkt 1

HCID 695150316-(4-Diethylamino-butoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid hexyl ester

Versuchsvorschrift

In analogy to example 3.9, Diethyl-[4-(1,2,3,4-tetrahydro-quinolin-6-yloxy)-butyl]-amine and hexylchloroformate were converted to yield 6-(4-Diethylamino-butoxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid hexyl ester as colorless oil, MS: 405 (MH+).

Quellen und Nachweise

ORD-Eintrag
ord-cd16ee370ecc4b2eaf1c63f5f2338f03
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06706751B2

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