HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Hydrochloric Acid → Ethyl 2-(piperidin-4-yl)acetate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Hydrochloric Acid | HCID 313 | — |
| Edukt | Ethyl pyridine-4-acetate | HCID 736321 | — |
| Katalysator | Platinum oxide (PtO) | HCID 82844 | — |
| Lösungsmittel | Ethanol | HCID 702 | — |
| Lösungsmittel | HCID 178418361 | HCID 178418361 | — |
| Produkt | Ethyl 2-(piperidin-4-yl)acetate | HCID 2760465 | 162,3% |
Reaktionsschritte
16.5 g (0.1 mol) Ethyl 4-pyridylacetate, 8.4 mL (0.1 mol) 12N hydrochloric acid and 2.5 g platinum oxide were dissolved in absolute ethanol and hydrogenated at 40 psi hydrogen on a Parr shaker. After 1 hour, the contents of the vessel were filtered and concentrated in vacuo yielding 27.79 g of ethyl 4-piperidinylacetate.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05242924 |
| Quelldatensatz | uspto-grants-1993_09 |
| ORD ID | ord-4bf57d14da074ba286dc99dcf47db4ab |
| Quellennotiz | uspto-grants-1993_09 |