HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Letrozole → HCID 178509721, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Letrozole | HCID 3902 | — |
| Edukt | 1H-1,2,4-Triazole | HCID 9257 | — |
| Edukt | 4-(Bromomethyl)benzonitrile | HCID 86996 | — |
| Produkt | HCID 178509721 | HCID 178509721 | — |
Reaktionsschritte
U.S. Pat. No. 4,978,672 (“the '672 patent”) describes a process for preparing letrozole by reacting α-bromo-4-tolunitrile with 1,2,4-triazole to produce 4-[1-(1,2,4-triazolyl)methyl]-benzonitrile, and reacting the product with 4-fluorobenzonitrile to obtain letrozole.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07538230B2 |
| Quelldatensatz | uspto-grants-2009_05 |
| ORD ID | ord-7c41f7faad9440d2a073c3b280f93bd9 |
| Quellennotiz | uspto-grants-2009_05 |