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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 495569Erstellt: 24. Oktober 2026

(2-Amino-5-chlorophenyl)-pyridin-4-yl methanone → N-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-(1,1-dimethyl-propyl)-benzenesulfonamide

https://huagongshe.com/de/reaction/495569

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(2-Amino-5-chlorophenyl)-pyridin-4-yl methanoneHCID 10214538—
Edukt4-(2-Methylbutan-2-yl)benzene-1-sulfonyl chlorideHCID 22281976—
ProduktN-[4-Chloro-2-(pyridine-4-carbonyl)-phenyl]-4-(1,1-dimethyl-propyl)-benzenesulfonamideHCID 10026396—

Reaktionsschritte

The title compound was prepared according to the general procedure for the synthesis of N-Aryl-benzenesulfonamides previously described using 116 mg of (2-amino-5-chloro-phenyl)-pyridin-4-yl-methanone and 123 mg of 4-(1,1-dimethyl-propyl)-benzenesulfonyl chloride. 1H-NMR (400 MHz, CDCl3): δ 0.59 (t, 3H, J=7.2 Hz), 1.23 (s, 6H), 1.61 (q, 2H, J=7.2 Hz), 7.28 (d, 1H, J=2.8 Hz), 7.36 (m, 2H), 7.53 (m, 3H), 7.67-7.74 (m, 3H), 8.84 (m, 2H), 10.14 (s, 1H). MS: m/z 443.9 (M++1).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06939885B2
Quelldatensatzuspto-grants-2005_09
ORD IDord-b7b48fd2ccb344a39ec6c901ecc130c5
Quellennotizuspto-grants-2005_09