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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 495627Erstellt: 25. Oktober 2026

Ethyl 4-chlorobenzyl[2,4-dinitro-6-(trifluoromethyl)phenyl]carbamate → Ethyl 4-chlorobenzyl[2,4-diamino-6-(trifluoromethyl)phenyl]carbamate

https://huagongshe.com/reaction/495627

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktEthyl 4-chlorobenzyl[2,4-dinitro-6-(trifluoromethyl)phenyl]carbamateHCID 20827746—
KatalysatorPalladiumHCID 23938—
LösungsmittelEthyl AcetateHCID 8857—
ProduktEthyl 4-chlorobenzyl[2,4-diamino-6-(trifluoromethyl)phenyl]carbamateHCID 2082774597,4%

Reaktionsschritte

Ethyl 4-chlorobenzyl[2,4-dinitro-6-(trifluoromethyl)phenyl]carbamate (294.7 mg) was dissolved in ethyl acetate (20 ml), and to the solution was added 10% Pd—C (267.7 mg). The reaction mixture was stirred under hydrogen atmosphere for 7 hours. The catalyst was filtered, and washed with ethyl acetate. The filtrate was concentrated in vacuo to give the title compound (248.7 mg).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06939887B2
Quelldatensatzuspto-grants-2005_09
ORD IDord-22e9506486f448879edec20695904024
Quellennotizuspto-grants-2005_09