HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3,5-Bis(trifluoromethyl)benzaldehyde → cis-4-(3,5-Bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3,5-Bis(trifluoromethyl)benzaldehyde | HCID 136247 | — |
| Edukt | cis-4-Amino-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl ester | HCID 69623683 | — |
| Produkt | cis-4-(3,5-Bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl ester | HCID 131723997 | — |
Reaktionsschritte
treating said cis-4-amino-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester first with 3,5-bis-trifluoromethyl-benzaldehyde under acidic conditions followed by a reducing agent to form cis-4-(3,5-bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester;
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06706881B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-4255667a58b641f4b7711a7a1e159ac1 |
| Quellennotiz | uspto-grants-2004_03 |