Sodium Hydroxide → 1-(Methoxycarbonyl)cyclopropane-1-carboxylic acid

HRID 496054Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 496054
[OH-].[Na+].[C:3]1([C:10]([O-:12])=[O:11])([C:6]([O:8][CH3:9])=[O:7])[CH2:5][CH2:4]1>CO>[CH3:9][O:8][C:6]([C:3]1([C:10]([OH:12])=[O:11])[CH2:5][CH2:4]1)=[O:7]

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 22325078Monomethyl cyclopropane-1,1-dicarboxylate

Produkt 1

HCID 138618231-(Methoxycarbonyl)cyclopropane-1-carboxylic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel

Versuchsvorschrift

1.45 liters of 1N sodium hydroxide solution are added to a solution, cooled to 5° C., of 1.45 ml of methyl 1,1-cyclopropanedicarboxylate in 2.5 liters of methanol. After stirring for 4 days at ambient temperature, the mixture is three-quarters concentrated, extracted with ether and then treated in customary manner, allowing the expected product to be isolated.

Aufarbeitung

  1. concentrationconcentrated
  2. extractionextracted with ether
  3. additiontreated in customary manner
  4. customto be isolated

Quellen und Nachweise

ORD-Eintrag
ord-4a70eccecef643dd8b83003fe0b11ca1
Quelldatensatz
uspto-grants-2005_09
Patentnummer
US06943184B2

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