Potassium Iodide → 1-(Dimethylamino)cyclopropaneacetonitrile

Reaktionsgleichung

Cl.Cl[CH2:3][C:4]1([N:7]([CH3:9])[CH3:8])[CH2:6][CH2:5]1.[C-:10]#[N:11].[Na+].[I-].[K+].C(=O)([O-])[O-].[Na+].[Na+].[Cl-].[Na+]>CS(C)=O>[CH3:8][N:7]([CH3:9])[C:4]1([CH2:3][C:10]#[N:11])[CH2:6][CH2:5]1

Komponenten

Edukt 5

HCID 4875Potassium Iodide

HCID 5234Sodium Chloride

HCID 8929Sodium Cyanide

HCID 10340Sodium Carbonate

HCID 22325122HCID 22325122, Verbindung

Produkt 1

HCID 223251211-(Dimethylamino)cyclopropaneacetonitrile

Reagenzien, Katalysatoren, Lösungsmittel 1

Versuchsvorschrift

30.3 g of the compound obtained in Step 1 are added to a solution of 43 g of sodium cyanide and 3.5 g of potassium iodide in 400 ml of dimethyl sulphoxide. After stirring for 20 hours at ambient temperature, 490 ml of 10% aqueous sodium carbonate solution and then sodium chloride are added. The mixture is extracted with ether. After conventional treatment of the organic phases, chromatography over silica gel allows the expected product to be isolated.