Bicyclo(2.2.1)heptane-2-methanol → Bicyclo[2.2.1]heptane-2-carbaldehyde

Temperatur

2.5 °C

A stirred suspension of 2-norbornylmethanol (0.5 ml; 5.8 mmol) and PCC on Al2O3* in CH2Cl2 (25 ml) was stirred at 2-3° C. for 1 h and allowed to slowly warm up to rt. The reaction mixture was filtered and the solid material washed with CH2Cl2 (2×25 ml). The combined organic fractions were adsorbed onto silica and chromatographed to give 300 mg (42%) product as an oil.

1. temperatureto slowly warm up to rt
2. filtrationThe reaction mixture was filtered
3. washthe solid material washed with CH2Cl2 (2×25 ml)
4. customchromatographed

ORD-Eintrag

ord-99da1fecffe54b5291694c2e35173483

Quelldatensatz

uspto-grants-2005_09

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US06943159B1