L-Methionine, methyl ester, hydrochloride → Methyl 2-[(2-benzyl-4-nitro-benzoyl)amino]-4-methylsulfanyl-butyrate
Reaktionsgleichung
[CH2:1]([C:8]1[CH:16]=[C:15]([N+:17]([O-:19])=[O:18])[CH:14]=[CH:13][C:9]=1[C:10]([OH:12])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[CH3:21][O:22][C:23](=[O:30])[C@H:24]([CH2:26][CH2:27][S:28][CH3:29])[NH2:25]>>[CH2:1]([C:8]1[CH:16]=[C:15]([N+:17]([O-:19])=[O:18])[CH:14]=[CH:13][C:9]=1[C:10]([NH:25][CH:24]([CH2:26][CH2:27][S:28][CH3:29])[C:23]([O:22][CH3:21])=[O:30])=[O:12])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Komponenten
3
Versuchsvorschrift
Compound 29 (2.45 mmol) was coupled with L-methionine methyl ester hydrochloride (540 mg, 2.7 mmol) to give methyl 2-[(2-benzyl-4-nitro-benzoyl)amino]-4-methylsulfanyl-butyrate (compound 30).
Quellen und Nachweise
- ORD-Eintrag
- ord-4e8f88e7e49242fd9b100c99f6e027fb
- Quelldatensatz
- uspto-grants-2005_09