Lithium Bromide → 1-(4-Bromo-2-phenyl-1-cyclopenten-1-yl)benzene

HRID 496750Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 496750
[C:1]1([C:7]2[CH2:8][CH:9](S(Cl)(=O)=O)[CH2:10][C:11]=2[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Li+].[Br-:23]>CC(C)=O>[Br:23][CH:9]1[CH2:8][C:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)=[C:11]([C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:10]1

Komponenten

4

Edukt 2

HCID 82050Lithium BromideHCID 223232413,4-Diphenyl-3-cyclopentene-1-sulfonyl chloride

Produkt 1

HCID 223232201-(4-Bromo-2-phenyl-1-cyclopenten-1-yl)benzeneAusbeute 82,6 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 180AcetoneLösungsmittel

Versuchsvorschrift

To a mixture of 3,4-diphenyl-3-cyclopentene-1-sulfonyl chloride (4 g) and 3 g of LiBr was added 70 mnL of acetone. Reaction mixture was stirred under reflux for 2.5 hr. Solvent was removed under reduced pressure and the residue was extracted with 60 mL of methylene chloride. Solution was filtered and solvent was removed under reduced pressure giving 3.1 g of product as brown-yellow solid.

Aufarbeitung

  1. customReaction mixture
  2. temperatureunder reflux for 2.5 hr
  3. customSolvent was removed under reduced pressure
  4. extractionthe residue was extracted with 60 mL of methylene chloride
  5. filtrationSolution was filtered
  6. customsolvent was removed under reduced pressure

Quellen und Nachweise

ORD-Eintrag
ord-ff2f1e4efbab428db113a92c9982d1af
Quelldatensatz
uspto-grants-2005_09
Patentnummer
US06946531B2

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