(4-Chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → tert-Butyl (2-amino-4-chloro-5-fluorophenyl)carbamate
Reaktionsgleichung
[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([F:14])[C:11]([Cl:15])=[CH:10][C:9]=1[N+:16]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:19])[NH:7][C:8]1[CH:13]=[C:12]([F:14])[C:11]([Cl:15])=[CH:10][C:9]=1[NH2:16])([CH3:4])([CH3:2])[CH3:3]Komponenten
3
Edukt 1
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
The title compound was prepared from (4-chloro-5-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A6) (16.48 g, 56.7 mmol) by hydrogenation with 5% Pt/C according to the general procedure J (method a). Obtained as a brown solid (14.78 g).
Quellen und Nachweise
- ORD-Eintrag
- ord-7a092a66c7cf4cacac512288c4178497
- Quelldatensatz
- uspto-grants-2005_09
- Patentnummer
- US06949542B2
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