[2-Nitro-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester → Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)phenyl]-,1,1-dimethylethyl ester

HRID 498200Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 498200
[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])[CH:11]=[CH:10][C:9]=1[N+:20]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pt]>[C:1]([O:5][C:6](=[O:23])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][C:16]([F:19])([F:18])[F:17])[CH:11]=[CH:10][C:9]=1[NH2:20])([CH3:4])([CH3:2])[CH3:3]

Komponenten

3

Edukt 1

HCID 69486960[2-Nitro-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester

Produkt 1

HCID 69487918Carbamic acid,[2-amino-5-(2,2,2-trifluoroethoxy)phenyl]-,1,1-dimethylethyl ester

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 23939PlatinumKatalysator

Versuchsvorschrift

The title compound was prepared from [2-nitro-5-(2,2,2-trifluoro-ethoxy)-phenyl]-carbamic acid tert-butyl ester (Example A13) by hydrogenation with 5% Pt/C according to the general procedure J (method a). Obtained as a light brown solid (13.157 g).

Quellen und Nachweise

ORD-Eintrag
ord-9956139c752a4369ae605ff1bcd06982
Quelldatensatz
uspto-grants-2005_09
Patentnummer
US06949542B2

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