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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 498341Erstellt: 25. Oktober 2026

(2-Amino-4-chloro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester → (4-Chloro-2-{3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/498341

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(2-Amino-4-chloro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 69487014—
Edukt3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489240—
Produkt(4-Chloro-2-{3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 86589306—

Reaktionsschritte

The title compound was prepared from (2-amino-4-chloro-5-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J24) (311 mg, 1.0 mmol) and 3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K15) (325 mg, 1.0 mmol) according to the general procedure M. Obtained as a light yellow oil (356 mg, 63%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06949542B2
Quelldatensatzuspto-grants-2005_09
ORD IDord-f4aed832cfb74df9a8606e1895aa0d48
Quellennotizuspto-grants-2005_09