Hydrochloric Acid → 6-Quinolinecarboxylic acid, ethyl ester

HRID 49926

Reaktionsgleichung

Reaktionsgleichung von HRID 49926
[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([OH:13])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.O1CCO[CH2:16][CH2:15]1.Cl>C(O)C>[N:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([O:13][CH2:15][CH3:16])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1

Komponenten

5

Edukt 3

HCID 313Hydrochloric AcidHCID 312751,4-DioxaneHCID 825716-Quinolinecarboxylic acid

Produkt 1

HCID 946706-Quinolinecarboxylic acid, ethyl ester

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Reaktionsbedingungen

Temperatur
70 °C

Versuchsvorschrift

4.9 g of quinoline-6-carboxylic acid was stirred in 80 ml of ethanol. 40 ml of dioxane containing 4 M of hydrogen chloride was added to the obtained mixture. After stirring at 70° C. overnight, the solvent was evaporated and the residue was treated with ethyl acetate as the extracting solvent by an ordinary method to obtain the title compound.

Aufarbeitung

  1. customthe solvent was evaporated
  2. additionthe residue was treated with ethyl acetate as the extracting solvent by an ordinary method

Quellen und Nachweise

ORD-Eintrag
ord-39bdd5917a824cf489af4d15fa464529
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06710056B2

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