Pyridine-2-carbonitrile → HCID 59750340, Verbindung

HRID 499270Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 499270
[CH3:1][O:2][C:3]1[C:4]([SH:12])=[C:5]([CH:9]=[CH:10][CH:11]=1)[C:6]([OH:8])=O.[C:13]([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=1)#[N:14]>N1C=CC=CC=1>[CH3:1][O:2][C:3]1[C:4]2[S:12][C:13]([C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][N:16]=3)=[N:14][C:6](=[O:8])[C:5]=2[CH:9]=[CH:10][CH:11]=1

Komponenten

4

Edukt 2

HCID 7522Pyridine-2-carbonitrileHCID 166556102-Mercapto-3-methoxybenzoic acid

Produkt 1

HCID 59750340HCID 59750340, VerbindungAusbeute 28 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1049PyridineLösungsmittel

Reaktionsbedingungen

Temperatur
135 °C

Versuchsvorschrift

A mixture of 3-methoxy-2-mercaptobenzoic acid (1.84 g, 10.0 mmol), 2-cyanopyridine (1.05 g, 10.2 mmol) and pyridine (30.0 ml) was refluxed at 135° C. for 18 hrs as described in Example 9. The mixture was concentrated. The obtained crystals were recrystallized from ethanol to give the titled compound (0.75 g, 28%).

Aufarbeitung

  1. concentrationThe mixture was concentrated
  2. customThe obtained crystals were recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-aa6d7a7476f4414b9e58fbba8e9dd439
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07767665B2

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