Triethylamine → HCID 59750109, Verbindung

HRID 499419Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 499419
[C:1]([C:3]1[CH:4]=[CH:5][C:6]([S:9][CH3:10])=[N:7][CH:8]=1)#[N:2].[C:11](OC)(=[O:19])[C:12]1[C:13](=[CH:15][CH:16]=[CH:17][CH:18]=1)[SH:14].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:10][S:9][C:6]1[N:7]=[CH:8][C:3]([C:1]2[S:14][C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[C:11](=[O:19])[N:2]=2)=[CH:4][CH:5]=1

Komponenten

5

Edukt 3

HCID 8471TriethylamineHCID 21009Benzoic acid, 2-mercapto-, methyl esterHCID 229395276-(Methylthio)nicotinonitrile

Produkt 1

HCID 59750109HCID 59750109, VerbindungAusbeute 31 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 1140TolueneLösungsmittel

Versuchsvorschrift

5-Cyano-2-methylthiopyridine (2.26 g, 15.0 mmol) and methyl thiosalicylate (5.05 g, 30.0 mmol) were dissolved in toluene (100 ml), and triethylamine (6.3 ml, 45.0 mmol) was added thereto. The reaction mixture was refluxed for 48 hrs. The solvent was evaporated. The residue was recrystallized from ethanol to give the titled compound (1.30 g, 31%) as pale yellow crystals.

Aufarbeitung

  1. temperatureThe reaction mixture was refluxed for 48 hrs
  2. customThe solvent was evaporated
  3. customThe residue was recrystallized from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-df5a09fb053b4d39a67d8fec9b82d43a
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07767665B2

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