Methyl iodide → Methyl 5-iodo-2-methoxybenzoate

HRID 49947

Reaktionsgleichung

Reaktionsgleichung von HRID 49947
CI.[I:3][C:4]1[CH:13]=[C:8]([C:9]([O:11][CH3:12])=[O:10])[C:7]([OH:14])=[CH:6][CH:5]=1.[C:15](=O)([O-])[O-].[K+].[K+]>CN(C)C=O>[CH3:15][O:14][C:7]1[CH:6]=[CH:5][C:4]([I:3])=[CH:13][C:8]=1[C:9]([O:11][CH3:12])=[O:10]

Komponenten

5

Edukt 3

HCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 248910Methyl 5-Iodosalicylate

Produkt 1

HCID 11011762Methyl 5-iodo-2-methoxybenzoate

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 6228DimethylformamideLösungsmittel

Versuchsvorschrift

Methyl iodide (0.29 ml, 4.68 mmol) was added to a mixture of 1.0 g (3.60 mmol) of methyl 5-iodosalicylate, 0.50 g (3.60 mmol) of potassium carbonate and 4 ml of dimethylformamide, and they were stirred at room temperature for 3 hours. The reaction mixture was filtered through Celite and then after-treated in by an ordinary method to obtain the title compound.

Aufarbeitung

  1. filtrationThe reaction mixture was filtered through Celite
  2. additionafter-treated in by an ordinary method

Quellen und Nachweise

ORD-Eintrag
ord-fa15a67265c94805a97b2ae90bc289f0
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06710056B2

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