Trifluoroacetic acid → HCID 22939317, Verbindung
Reaktionsgleichung
[Cl:1][C:2]1[CH:28]=[CH:27][C:5]2[C:6](=[O:26])[N:7]=[C:8]([C:10]3[CH:15]=[C:14]([CH2:16][CH2:17][NH:18]C(=O)OC(C)(C)C)[CH:13]=[CH:12][N:11]=3)[S:9][C:4]=2[CH:3]=1.[F:29][C:30]([F:35])([F:34])[C:31]([OH:33])=[O:32]>>[F:29][C:30]([F:35])([F:34])[C:31]([OH:33])=[O:32].[NH2:18][CH2:17][CH2:16][C:14]1[CH:13]=[CH:12][N:11]=[C:10]([C:8]2[S:9][C:4]3[CH:3]=[C:2]([Cl:1])[CH:28]=[CH:27][C:5]=3[C:6](=[O:26])[N:7]=2)[CH:15]=1Komponenten
3
Versuchsvorschrift
tert-Butyl 2-[2-(7-chloro-4-oxo-4H-1,3-benzothiazin-2-yl)-4-pyridyl]ethylcarbamate (0.36 g, 0.86 mmol) was dissolved in trifluoroacetic acid (10 ml), and the mixture was stirred at room temperature for 3 hrs. The solvent was evaporated, and the residue was recrystallized from methanol-diisopropyl ether to give the titled compound (0.33 g, 89%) as white crystals.
Aufarbeitung
- customThe solvent was evaporated
- customthe residue was recrystallized from methanol-diisopropyl ether