HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Mercaptoethanol → 5-[2-[(2-hydroxyethyl)thio]-2-(3-thienyl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-Mercaptoethanol | HCID 1567 | — |
| Edukt | (E)-2-methyl-2-phenyl-5-[2-(3-thienyl)ethenyl]-3(2H)-furanone | HCID 11300541 | — |
| Produkt | 5-[2-[(2-hydroxyethyl)thio]-2-(3-thienyl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one | HCID 10109185 | — |
Reaktionsschritte
Following the procedure of Method C, Example 1, (E)-2-methyl-2-phenyl-5-[2-(3-thienyl)ethenyl]-3(2H)-furanone was reacted with 2-mercapto-1-ethanol to provide 5-[2-[(2-hydroxyethyl)thio]-2-(3-thienyl)ethyl]-2-methyl-2-phenylfuran-3(2H)-one: 1H NMR (DMSO-d6) δ1.54 and 1.57 (singlets, 3H), 3.35-3.60 (m ovelapped with DMSO, ˜4H), 4.58 (m, 1H), 5.55 and 5.56 (overlapped singlets, 1H), 7.18-7.37 (m, 6H), 7.40-7.57 (m, 2H); MS(LR-ESI) m/z 361 (M+H calcd. for C19H21O3S2 361).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US06710078B2 |
| Quelldatensatz | uspto-grants-2004_03 |
| ORD ID | ord-00e7e9daefdb4e98ae68a50c74602a24 |
| Quellennotiz | uspto-grants-2004_03 |