Hydrochloric Acid → 2-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

HRID 501239Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 501239
[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH:22]C(=O)C)[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2].[ClH:26]>>[ClH:26].[CH:1]([C:4]1[S:8][C:7]([NH:9][S:10]([C:13]2[CH:14]=[C:15]3[C:19](=[CH:20][CH:21]=2)[CH2:18][CH:17]([NH2:22])[CH2:16]3)(=[O:12])=[O:11])=[N:6][N:5]=1)([CH3:3])[CH3:2]

Komponenten

3

Edukt 2

HCID 313Hydrochloric AcidHCID 57933501N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide

Produkt 1

HCID 672312832-Amino-indan-5-sulfonic acid (5-isopropyl-[1,3,4]thiadiazol-2-yl)-amide hydrochloride

Versuchsvorschrift

N-[5-(5-Isopropyl-[1,3,4]thiadiazol-2-ylsulfamoyl)-indan-2-yl]-acetamide (96 mg) was heated and stirred for 27 hours in 10 ml 2N hydrochloric acid at 100° C. After completion a clear solution occurred. This was evaporated to dryness and the solid residue was used without further purification.

Aufarbeitung

  1. customThis was evaporated to dryness
  2. customthe solid residue was used without further purification

Quellen und Nachweise

ORD-Eintrag
ord-5075e4d3dbed44eabd6eac14669eea2a
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07772257B2

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