Methanol--water (1/1) → 1,17-Biscyclohexylguanidino-9-azaheptadecane triacetate

HRID 5031

Reaktionsgleichung

Reaktionsgleichung von HRID 5031
I.I.[CH:3]1([N:9]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][NH:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH:30]2[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]2)[C:10]([NH2:12])=[NH:11])[CH2:8][CH2:7][CH2:6][CH2:5][CH2:4]1.[CH3:36][OH:37].[OH2:38]>>[C:36]([OH:38])(=[O:37])[CH3:3].[C:36]([OH:38])(=[O:37])[CH3:3].[C:36]([OH:38])(=[O:37])[CH3:3].[CH:3]1([N:9]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][NH:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH:30]2[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]2)[C:10]([NH2:12])=[NH:11])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1

Komponenten

3

Edukt 2

HCID 22242641Methanol--water (1/1)HCID 1317181081,17-Biscyclohexylguanidino-9-azaheptadecane dihydroiodide

Produkt 1

HCID 1317181061,17-Biscyclohexylguanidino-9-azaheptadecane triacetate

Versuchsvorschrift

10.2 g (0.011 mol) of 1,17-biscyclohexylguanidino-9-azaheptadecane dihydroiodide in 150 ml of methanol/water (1:1) were filtered through a column containing 250 g of ion exchanger (OH- form). The free guanidine base obtained after working up was dissolved in methanol and converted into the triacetate with excess glacial acetic acid.

Quellen und Nachweise

ORD-Eintrag
ord-4bb73f6b08114a6bb1231cd70986f4d3
Quelldatensatz
uspto-grants-1993_09
Patentnummer
US05242948

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