Hexane → HCID 178516446, Verbindung

HRID 503581Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 503581
CC1(C)O[C:6](=[O:8])[C:5](=[CH:9][NH:10][C:11]2[CH:16]=[CH:15][N:14]=[CH:13][CH:12]=2)C(=O)O1.CCCCCC>C1(OC2C=CC=CC=2)C=CC=CC=1>[N:10]1[C:11]2[C:12](=[CH:13][N:14]=[CH:15][CH:16]=2)[C:6]([OH:8])=[CH:5][CH:9]=1

Komponenten

4

Edukt 2

HCID 8058HexaneHCID 59427333HCID 59427333, Verbindung

Produkt 1

HCID 178516446HCID 178516446, Verbindung

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 7583Diphenyl EtherLösungsmittel

Versuchsvorschrift

A solution of 2,2-dimethyl-5-((pyridin-4-ylamino)methylene)-1,3-dioxane-4,6-dione (1.149 g, 4.63 mmol) in diphenyl ether was heated at 200° C. for 20 min, then cooled to RT. Hexane was added and the mixture was stirred at RT for 30 mins. The solid was filtered off and washed with hexane to furnish 1,6-naphthyridin-4-ol as an off-brown solid.

Aufarbeitung

  1. filtrationThe solid was filtered off
  2. washwashed with hexane

Quellen und Nachweise

ORD-Eintrag
ord-3f1d461f44504da29f96b66df178b6fe
Quelldatensatz
uspto-grants-2010_08
Patentnummer
US07776857B2

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