Indole → Methyl (E)-11-[2-(7-aza-1-indolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

HRID 5038

Reaktionsgleichung

Reaktionsgleichung von HRID 5038
Cl[CH2:2]/[CH:3]=[C:4]1/[C:5]2[CH:18]=[C:17]([C:19]([O:21][CH3:22])=[O:20])[CH:16]=[CH:15][C:6]=2[O:7][CH2:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]/1=2.[N:23]1[C:27]2[CH:28]=[CH:29][CH:30]=[CH:31][C:26]=2[NH:25][CH:24]=1.N1C2C(=CC=CC=2)C=C1>>[N:25]1([CH2:2]/[CH:3]=[C:4]2/[C:5]3[CH:18]=[C:17]([C:19]([O:21][CH3:22])=[O:20])[CH:16]=[CH:15][C:6]=3[O:7][CH2:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]/2=3)[C:24]2[C:30](=[CH:29][CH:28]=[CH:27][N:23]=2)[CH:31]=[CH:26]1

Komponenten

4

Edukt 3

HCID 798IndoleHCID 5798BenzimidazoleHCID 10448388Methyl (E)-11-(2-chloroethylidene)-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

Produkt 1

HCID 15704217Methyl (E)-11-[2-(7-aza-1-indolyl)ethylidene]-6,11-dihydrodibenz[b,e]oxepin-2-carboxylate

Versuchsvorschrift

In Examples 40 through 49, the products were prepared in a manner similar to Example 23, using Compound h and the corresponding benzimidazole or indole derivatives.

Aufarbeitung

  1. customIn Examples 40 through 49, the products were prepared in a manner similar to Example 23

Quellen und Nachweise

ORD-Eintrag
ord-c5ae183eb4bd4d98998488c4391b784a
Quelldatensatz
uspto-grants-1993_09
Patentnummer
US05242931

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