Naphthalene-2-sulfonamide → 2-ETHYL-5,7-DIMETHYL-3-{4-[2-({[(2-NAPHTHYLSULFONYL)AMINO]CARBONYL}AMINO)ETHYL]PHENYL}-3H-IMIDAZO[4,5-b]PYRIDINE

HRID 50428Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 50428
[C:1]1([C:35]2C=C[CH:38]=[CH:37][CH:36]=2)[CH:6]=[CH:5][C:4]([S:7]([NH:10][C:11]([NH:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[C:26]4=[N:27][C:28]([CH3:32])=[CH:29][C:30]([CH3:31])=[C:25]4[N:24]=[C:23]3[CH2:33][CH3:34])=[CH:18][CH:17]=2)=[O:12])(=[O:9])=[O:8])=[CH:3][CH:2]=1.C1C2C(=CC=CC=2)C=CC=1S(N)(=O)=O>>[CH2:33]([C:23]1[N:22]([C:19]2[CH:18]=[CH:17][C:16]([CH2:15][CH2:14][NH:13][C:11]([NH:10][S:7]([C:4]3[CH:5]=[CH:6][C:1]4[C:2](=[CH:38][CH:37]=[CH:36][CH:35]=4)[CH:3]=3)(=[O:8])=[O:9])=[O:12])=[CH:21][CH:20]=2)[C:26]2=[N:27][C:28]([CH3:32])=[CH:29][C:30]([CH3:31])=[C:25]2[N:24]=1)[CH3:34]

Komponenten

3

Edukt 2

HCID 232997Naphthalene-2-sulfonamideHCID 218756193-{4-[2-({[(4-biphenylsulfonyl)amino]carbonyl}amino)ethyl]phenyl}-2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine

Produkt 1

HCID 218756032-ETHYL-5,7-DIMETHYL-3-{4-[2-({[(2-NAPHTHYLSULFONYL)AMINO]CARBONYL}AMINO)ETHYL]PHENYL}-3H-IMIDAZO[4,5-b]PYRIDINE

Versuchsvorschrift

The title compound was prepared according to the procedure described in step 2 of Example 18 from phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylcarbamate (step 1 of Example 18) and 2-naphtylsulfonamide.

Quellen und Nachweise

ORD-Eintrag
ord-a5e03d6a1bcf45e49f33a37ecfc227c5
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06710054B2

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