HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid → (S)-2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(3-methyl-oxetan-3-ylmethyl)-1H-imidazol-4-yl]-amide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid | HCID 21112802 | — |
| Edukt | 1-(3-Methyl-oxetan-3-ylmethyl)-4-nitro-1H-imidazole | HCID 68464961 | — |
| Produkt | (S)-2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid [1-(3-methyl-oxetan-3-ylmethyl)-1H-imidazol-4-yl]-amide | HCID 16113790 | — |
Reaktionsschritte
1-(3-Methyl-oxetan-3-ylmethyl)-4-nitro-1H-imidazole was reduced and then coupled with 2-(6,8-Difluoro-1,2,3,4-tetrahydro-naphthalen-2-ylamino)-pentanoic acid (U.S. Ser. No. 11/078,898 filed Mar. 11, 2005) to afford the title compound: MS 433.3 m/z (M+1).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07781435B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-521a63e8764f41b497387d8ac046c5df |
| Quellennotiz | uspto-grants-2010_08 |