HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-(Chloromethyl)pyridine → (6-Chloro-1-pyridin-3-ylmethyl-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 3-(Chloromethyl)pyridine | HCID 18358 | — |
| Edukt | (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 16062188 | — |
| Produkt | (6-Chloro-1-pyridin-3-ylmethyl-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 16062191 | — |
Reaktionsschritte
Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with commercially available 3-chloromethyl-pyridine gave the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07781436B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-79c90cc6c8c94edb950381b681cd78a3 |
| Quellennotiz | uspto-grants-2010_08 |