HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-chloro-N-methylacetamide → 2-{6-Chloro-3-[4-(2-trifluoromethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 2-chloro-N-methylacetamide | HCID 66773 | — |
| Edukt | (6-chloro-1H-indol-3-yl)-[4-(2-trifluoromethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 59429664 | — |
| Produkt | 2-{6-Chloro-3-[4-(2-trifluoromethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N-methyl-acetamide | HCID 16062830 | — |
Reaktionsschritte
Analogous to general procedure I, the coupling of (6-chloro-1H-indol-3-yl)-[4-(2-trifluoromethoxy-phenyl)-piperidin-1-yl]-methanone (prepared herein) with (commercially available) 2-chloro-N-methyl-acetamide gave the title compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07781436B2 |
| Quelldatensatz | uspto-grants-2010_08 |
| ORD ID | ord-9ccaf909647948a9bbb54841508bd4e1 |
| Quellennotiz | uspto-grants-2010_08 |