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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 50548Erstellt: 25. Oktober 2026

2-Aminopyridine → N-alpha-t-BOC-L-phenylalanine 2-aminopyridine

https://huagongshe.com/reaction/50548

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-AminopyridineHCID 10439—
EduktDicyclohexylcarbodiimideHCID 10868—
EduktL-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-HCID 77857—
ProduktN-alpha-t-BOC-L-phenylalanine 2-aminopyridineHCID 131722899—

Reaktionsschritte

The acylated phenylalanine anilide imprint molecule was synthesized in three steps. (1) N-α-t-BOC-L-phenylalanine was coupled with 2-aminopyridine using DCC to give N-α-t-BOC-L-phenylalanine-2-aminopyridine. (2) The α-amine was then deprotected with TFA to give N-α-L-phenylalanine-2-aminopyridine. (3) To create a compound having the properties of a surfactant, the free amine was then acylated with decanoic acid using DCC to give N-α-decyl-L-phenylalanine-2-aminopyridine.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS06713416B2
Quelldatensatzuspto-grants-2004_03
ORD IDord-e4e5c5db7a4045c7934fd55d1008f962
Quellennotizuspto-grants-2004_03