Methyl 4'-(benzyloxy)-2',6,6'-trimethylbiphenyl-3-carboxylate → Methyl 4'-hydroxy-2',6,6'-trimethylbiphenyl-3-carboxylate
Reaktionsgleichung
C([O:8][C:9]1[CH:14]=[C:13]([CH3:15])[C:12]([C:16]2[C:21]([CH3:22])=[CH:20][CH:19]=[C:18]([C:23]([O:25][CH3:26])=[O:24])[CH:17]=2)=[C:11]([CH3:27])[CH:10]=1)C1C=CC=CC=1>[C].[Pd].C(O)C>[OH:8][C:9]1[CH:14]=[C:13]([CH3:15])[C:12]([C:16]2[C:21]([CH3:22])=[CH:20][CH:19]=[C:18]([C:23]([O:25][CH3:26])=[O:24])[CH:17]=2)=[C:11]([CH3:27])[CH:10]=1Komponenten
4
Versuchsvorschrift
A mixture of methyl 4′-(benzyloxy)-2′,6,6′-trimethylbiphenyl-3-carboxylate (255 mg, 0.71 mmol), 10% palladium-carbon (50% water-containing product, 25.5 mg) and ethanol (3 mL) was stirred overnight under a hydrogen atmosphere at room temperature. The catalyst was filtered off, and the filtrate was concentrated under reduced pressure. The residue was again subjected to the above-mentioned conditions (10% palladium-carbon (50% water-containing product, 127 mg), stirring time 2 hr) to give the title compound (199 mg, yield 100%) as a colorless oil.