HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Methyl fluorosulfate → (2S)-1,1-Dimethyl-2-(4-methoxybenzylthiomethyl)pyrrolidinium fluorosulfonate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Methyl fluorosulfate | HCID 9870 | — |
| Edukt | (2S)-2-(4-Methoxybenzylthiomethyl)-1-methylpyrrolidine | HCID 57048351 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | (2S)-1,1-Dimethyl-2-(4-methoxybenzylthiomethyl)pyrrolidinium fluorosulfonate | HCID 14880299 | — |
Reaktionsschritte
The procedure described in Preparation 5-(5) was repeated, but using 740 mg of (2S)-2-(4-methoxybenzylthiomethyl)-1-methylpyrrolidine and 243 μl of methyl fluorosulfonate in the presence of 22 ml of methylene chloride, to afford 1.0 g of the title compound as crystals, melting at 150°-153° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US05242914 |
| Quelldatensatz | uspto-grants-1993_09 |
| ORD ID | ord-5a0095e69f164f00815bcbd1c99cbbde |
| Quellennotiz | uspto-grants-1993_09 |