Dipropan-2-yl(3-nitrophenyl)phosphonate → Dipropan-2-yl(3-aminophenyl)phosphonate
Reaktionsgleichung
NC1C=CC(P(=O)(OC(C)C)OC(C)C)=CC=1.[N+:18]([C:21]1[CH:22]=[C:23]([P:27](=[O:36])([O:32][CH:33]([CH3:35])[CH3:34])[O:28][CH:29]([CH3:31])[CH3:30])[CH:24]=[CH:25][CH:26]=1)([O-])=O>>[NH2:18][C:21]1[CH:22]=[C:23]([P:27](=[O:36])([O:28][CH:29]([CH3:31])[CH3:30])[O:32][CH:33]([CH3:35])[CH3:34])[CH:24]=[CH:25][CH:26]=1Komponenten
3
Versuchsvorschrift
Prepared according to the procedure described for dipropan-2-yl (4-aminophenyl)phosphonate using dipropan-2-yl (3-nitrophenyl)phosphonate. Yield: 45%. 1H-NMR (DMSO-d6, 400 MHz): δ=1.15 (d, J=6.4 Hz, 6 H), 1.24 (d, J=6.4 Hz, 6 H), 4.45-4.50 (m, 2 H), 5.35 (s, br, 2 H), 6.70-6.77 (m, 2 H), 6.58 (d, J=8.0 Hz, 1 H), 7.10-7.25 (m, 1 H). MS: m/z 257.97 [MH+].
Aufarbeitung
- customPrepared