Trifluoroacetic acid → 7-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

HRID 511321Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 511321
C(OC([NH:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1)=O)(C)(C)C.C(O)(C(F)(F)F)=O>>[NH2:8][C:9]1[C:17]2[C:16](=[O:18])[N:15]([CH3:19])[CH2:14][C:13]=2[C:12]([C:20]([OH:22])=[O:21])=[CH:11][CH:10]=1

Komponenten

3

Edukt 2

HCID 6422Trifluoroacetic acidHCID 672564057-[(Tert-butoxycarbonyl)amino]-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

Produkt 1

HCID 672542797-amino-2-methyl-1-oxo-2,3-dihydro-1H-isoindole-4-carboxylic acid

Versuchsvorschrift

The title compound was prepared by deprotecting Compound 116C with TFA. The crude product was taken on to the next step without purification.

Aufarbeitung

  1. customThe crude product was taken on to the next step without purification

Quellen und Nachweise

ORD-Eintrag
ord-90ff44e86d8349c4b9abbd8ada76d88d
Quelldatensatz
uspto-grants-2015_08
Patentnummer
US09096624B2

Notizen zur Reaktion

Wird geladen…