HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nitric Acid → 3-(3-chloro-4-nitro-1H-pyrazol-1-yl)pyridine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Nitric Acid | HCID 944 | — |
| Edukt | Sulfuric Acid | HCID 1118 | — |
| Edukt | 3-(3-chloro-1H-pyrazol-1-yl)pyridine | HCID 67499540 | — |
| Produkt | 3-(3-chloro-4-nitro-1H-pyrazol-1-yl)pyridine | HCID 67500148 | — |
Reaktionsschritte
In step d of Scheme 1, compound (5b) is nitrated with nitric acid (HNO3), preferably in the presence of sulfuric acid (H2SO4) to yield 3-(3-chloro-4-nitro-1H-pyrazol-1-yl)pyridine (5c). The nitration may be conducted at temperatures from about −10° C. to about 30° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09102654B2 |
| Quelldatensatz | uspto-grants-2015_08 |
| ORD ID | ord-bf25e7b693254f6f9399714fb9ce2282 |
| Quellennotiz | uspto-grants-2015_08 |